Description

2-(2,5-Dimethylthiophen-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acids/esters, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
• Organic Light-Emitting Diodes (OLEDs): A precursor for synthesizing electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organometallic complexes.
• Material Science Research: Used to create monomers and functional units for conductive polymers, organic semiconductors, and other advanced materials.

Basic Information

Product Name	2-(2,5-Dimethylthiophen-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	942070-20-4
Molecular Formula	C14H23BO2S
Molecular Weight	266.21 g/mol
Synonyms	2-(2,5-Dimethyl-3-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dimethylthiophene; Pinacol (2,5-dimethylthiophen-3-yl)boronate; (2,5-Dimethylthiophen-3-yl)boronic acid pinacol ester; 2,5-Dimethyl-3-boronic acid pinacol ester thiophene
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dimethylthiophen-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for cGMP and research-grade chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.