Description

5-Chlorothiophene-2,4-Diboronic Acid Pinacol Ester is a high-purity, multi-functional boronic ester building block essential for modern synthetic chemistry. This compound is a critical reagent for constructing complex molecular architectures via cross-coupling reactions, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating thiophene-based derivatives with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used to build complex heterocyclic structures found in advanced pesticides and herbicides.
• Organic Electronics: Serves as a monomer or building block for constructing conjugated polymers and small molecules used in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Material Science Research: Enables the development of novel organic frameworks, ligands for catalysis, and specialty polymers with specific electronic or optical properties.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and bioconjugates due to the versatility of the boronic ester functional groups.

Basic Information

Product Name	5-Chlorothiophene-2,4-Diboronic Acid Pinacol Ester
CAS No.	942070-16-8
Molecular Formula	C16H21B2ClO4S
Molecular Weight	374.88 g/mol
Synonyms	5-Chloro-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 2,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-chlorothiophene; 5-Chlorothiophene-2,4-diyldiboronic Acid Bis(pinacol) Ester; 5-Chloro-2,4-di(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; Thiophene-2,4-diboronic acid pinacol ester, 5-chloro- derivative
EINECS	Contact for details

Quality Control

Our 5-Chlorothiophene-2,4-Diboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry-standard analytical methods including NMR, HPLC, and GC-MS for verification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.