Description

4-Bromothiophene-2-Boronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a versatile reagent for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiophene and biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs), semiconductors, and conductive polymers.
• Chemical Biology & Medicinal Chemistry: Serves as a crucial reagent in library synthesis for high-throughput screening and structure-activity relationship (SAR) studies.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Item	Details
Product Name	4-Bromothiophene-2-Boronic Acid Pinacol Ester
CAS No.	942070-06-6
Molecular Formula	C10H14BBrO2S
Molecular Weight	289.00 g/mol
Synonyms	4-Bromo-2-thienylboronic acid pinacol ester; 2-(4-Bromothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromothiophene-2-boronic acid neopentyl glycol ester (common name); (4-Bromothiophen-2-yl)boronic acid pinacol ester; Pinacol 4-Bromo-2-thienylboronate; 942070-06-6; BRN 8514336
EINECS	Contact for details

Quality Control

Our 4-Bromothiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We adhere to industry best practices and can support projects requiring material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.