Description

2,2'-(3-Bromothiophene-2,5-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is a high-purity, bifunctional boronic ester derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive platform for constructing complex molecular architectures, particularly through cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable intermediates for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing thiophene and heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of new generation herbicides, fungicides, and insecticides that require specific thiophene-based structures.
• Organic Electronic Materials: Building block for the synthesis of conjugated polymers and small molecules used in Organic Light-Emitting Diodes (OLEDs), Organic Photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Serves as a starting material for creating specialized bidentate ligands and organometallic catalysts.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on palladium-catalyzed C-C bond formation and heterocyclic chemistry.
• Polymer Modification: Enables the functionalization of polymer backbones to introduce boronic ester handles for further chemical modification or sensing applications.

Basic Information

Product Name	2,2'-(3-Bromothiophene-2,5-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane)
CAS No.	942070-04-4
Molecular Formula	C18H28BBrO4S
Molecular Weight	431.19 g/mol
Synonyms	3-Bromo-2,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 2,5-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-bromothiophene; 3-Bromo-2,5-di(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 3-Bromothiophene-2,5-diyldiboronic acid bis(pinacol) ester; 3-Bromo-2,5-bis(pinacolatoboryl)thiophene; Pinacol 3-Bromothiophene-2,5-diyldiboronate; 942070-04-4
EINECS	Contact for details

Quality Control

Our 2,2'-(3-Bromothiophene-2,5-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.