Description

2-(4-Bromo-5-Chlorothiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron building block, specifically a pinacol boronic ester, critical for modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality intermediates for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates containing functionalized thiophene rings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate halogenated thiophene motifs.
• Material Science: Serves as a precursor for creating conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research: A versatile reagent for academic and industrial research in palladium-catalyzed cross-coupling reactions to create complex, bespoke organic molecules.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Product Name	2-(4-Bromo-5-Chlorothiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	942070-02-2
Molecular Formula	C10H14BBrClO2S
Molecular Weight	339.45 g/mol
Synonyms	4-Bromo-5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; (4-Bromo-5-chlorothiophen-2-yl)boronic acid pinacol ester; 2-(4-Bromo-5-chloro-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(4-bromo-5-chloro-2-thienyl)-1,3,2-dioxaborolane; Pinacol (4-Bromo-5-chlorothiophen-2-yl)boronate; 942070-02-2; 4-Bromo-5-chlorothiophene-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2-(4-Bromo-5-Chlorothiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.