Description

3,4,5-Trichlorophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, specifically designed as a key synthetic intermediate for advanced organic synthesis. Its primary value lies in providing a stable, air- and moisture-tolerant form of the reactive boronic acid, enabling more efficient and reliable cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and robust building blocks for constructing complex molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical building block for the formation of biaryl and heterobiaryl structures, which are core motifs in many active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate: Used in the research, development, and scale-up synthesis of novel drug candidates, particularly those requiring substituted phenyl rings.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and functional materials.
• Material Science Research: Used in the synthesis of organic electronic materials, such as those for OLEDs or organic semiconductors, where defined molecular architecture is crucial.
• Chemical Biology & Proteomics: Can be utilized as a handle for bioconjugation or in the synthesis of molecular probes.

Basic Information

Product Name	3,4,5-Trichlorophenylboronic Acid, Pinacol Ester
CAS No.	942069-95-6
Molecular Formula	C12H14BCl3O2
Molecular Weight	305.41 g/mol
Synonyms	2-(3,4,5-Trichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3,4,5-Trichlorophenyl)boronic acid pinacol ester; 3,4,5-Trichlorophenylboronic acid pinacol ester; 3,4,5-Trichloro-1-boronophenyl pinacol ester; Pinacol (3,4,5-Trichlorophenyl)boronate; 3,4,5-Trichlorobenzeneboronic acid pinacol ester; B-(3,4,5-Trichlorophenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3,4,5-Trichlorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.