Description

2-(3,5-Dichloro-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing complex biaryl motifs common in modern therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific chlorinated aromatic structures.
• Material Science: Serves as a precursor for organic electronic materials, such as polymers and small molecules used in OLEDs, OFETs, and photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular libraries via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Preparation: Can be utilized to synthesize specialized ligands or functionalized materials for catalytic systems.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and dyes.

Basic Information

Product Name	2-(3,5-Dichloro-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	942069-73-0
Molecular Formula	C13H17BCl2O2
Molecular Weight	287.99 g/mol
Synonyms	(3,5-Dichloro-4-methylphenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[3,5-dichloro-4-methylphenyl]-1,3,2-dioxaborolane; 2-(3,5-Dichloro-p-tolyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3,5-Dichloro-4-methylphenyl)pinacolboronate; Pinacol (3,5-dichloro-4-methylphenyl)boronate; 3,5-Dichloro-4-methylbenzeneboronic acid pinacol ester; B-(3,5-Dichloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dichloro-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.