Description

2-(3,4-Dichloro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, synthetically valuable boronic ester derivative, widely recognized as a key building block in modern organic synthesis. Its primary value lies in enabling efficient and selective carbon-carbon bond formation, which is critical for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a substituted phenyl moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific, multi-step synthetic projects requiring precise boronic ester chemistry.

Basic Information

Item	Details
Product Name	2-(3,4-Dichloro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	942069-71-8
Molecular Formula	C13H17BCl2O2
Molecular Weight	287.99 g/mol
Synonyms	(3,4-Dichloro-5-methylphenyl)boronic acid pinacol ester; 2-(3,4-Dichloro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,4-Dichloro-5-methylbenzeneboronic acid pinacol ester; (3,4-Dichloro-5-methylphenyl)pinacolboronate; 942069-71-8; 3,4-Dichloro-5-methylphenylboronic acid pinacol ester; 5-Methyl-3,4-dichlorophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dichloro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP guidelines where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged operations to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.