Description

2-(3,5-Dichloro-4-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for Suzuki-Miyaura coupling and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the introduction of the dichloro-methoxyphenyl moiety is required.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a model substrate for testing new catalytic systems in cross-coupling chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, leveraging its boronate functionality for bioconjugation strategies.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-(3,5-Dichloro-4-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	942069-69-4
Molecular Formula	C13H17BCl2O3
Molecular Weight	303.00 g/mol
Synonyms	(3,5-Dichloro-4-methoxyphenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(3,5-dichloro-4-methoxyphenyl)-1,3,2-dioxaborolane; 3,5-Dichloro-4-methoxybenzeneboronic acid pinacol ester; Pinacol (3,5-dichloro-4-methoxyphenyl)boronate; B-(3,5-Dichloro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 942069-69-4; Boronic acid, B-(3,5-dichloro-4-methoxyphenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dichloro-4-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.