Description

2-(4-Bromo-3,5-Dichlorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, a fundamental step in constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality reagents for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds containing a halogenated biphenyl core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Organic Light-Emitting Diodes (OLEDs): Acts as a monomer or intermediate in the development of novel electron-transport materials and emissive layer components.
• Liquid Crystal & Polymer Chemistry: Employed to create functionalized aromatic monomers for specialty polymers and liquid crystal displays (LCDs).
• Material Science Research: Facilitates the development of novel organic frameworks, covalent organic polymers (COPs), and other advanced functional materials.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	2-(4-Bromo-3,5-Dichlorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	942069-45-6
Molecular Formula	C12H14BBrCl2O2
Molecular Weight	352.86 g/mol
Synonyms	4-Bromo-3,5-dichlorophenylboronic acid pinacol ester; (4-Bromo-3,5-dichlorophenyl)boronic acid pinacol ester; 4-Bromo-3,5-dichlorobenzene-1-boronic acid pinacol ester; 2-(4-Bromo-3,5-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 942069-45-6; B-(4-Bromo-3,5-dichlorophenyl)boronic acid pinacol ester; Pinacol (4-bromo-3,5-dichlorophenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-3,5-Dichlorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.