Description

Di-2-Methoxyethyl Azodicarboxylate is a specialized azodicarboxylate ester derivative, valued for its role as a versatile reagent in organic synthesis, particularly in Mitsunobu and other coupling reactions. Its primary commercial value lies in enabling efficient, high-yield transformations for constructing complex molecular architectures under mild conditions. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks.

Application

• Key reagent in Mitsunobu reactions for the inversion of stereocenters and formation of esters, ethers, and thioethers.
• Facilitates dehydrative coupling processes in the synthesis of active pharmaceutical ingredients (APIs) and intermediates.
• Used in the preparation of functionalized polymers and specialty materials through azo-group incorporation.
• Employed in peptide chemistry and other condensation reactions requiring mild, neutral conditions.
• Serves as a radical initiator precursor in controlled polymerization and cross-linking applications.
• Valuable in academic and industrial R&D for methodology development and complex molecule construction.

Basic Information

Product Name	Di-2-Methoxyethyl Azodicarboxylate
CAS No.	940868-64-4
Molecular Formula	C8H14N2O6
Molecular Weight	234.21 g/mol
Synonyms	Bis(2-methoxyethyl) Azodicarboxylate; Azodicarboxylic Acid Bis(2-methoxyethyl) Ester; 2-Methoxyethyl Azodicarboxylate; DMAD Analog; Di(2-methoxyethyl) Diazenedicarboxylate; Azodicarboxylic Acid Di(2-methoxyethyl) Ester
EINECS	Contact for details

Quality Control

Our Di-2-Methoxyethyl Azodicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including chromatography and spectroscopic methods, to confirm identity and purity. Certificates of Analysis (COA) documenting all critical quality parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and shelf life. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.