Description

(Z,5S)-5-Acetamido-5-Carboxy-1-Diazonio-Pent-1-En-2-Olate is a specialized diazonium compound with a unique chiral and unsaturated structure, serving as a critical synthetic intermediate. Its value lies in enabling precise chemical transformations, particularly in the synthesis of complex, biologically active molecules where stereochemistry and functional group compatibility are paramount. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to innovate in targeted synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring specific stereochemical configurations.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and plant growth regulators with enhanced specificity.
• Peptidomimetic Synthesis: Serves as a building block for creating peptide analogs and mimetics due to its acetamido and carboxy functional groups.
• Bioconjugation Chemistry: Utilized in linker technologies for attaching payloads to antibodies, proteins, or other biomolecules in ADC (Antibody-Drug Conjugate) development.
• Material Science Research: Investigated for incorporation into specialty polymers or as a surface modification agent.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, particularly involving diazonium chemistry and chiral induction.

Basic Information

Product Name	(Z,5S)-5-Acetamido-5-Carboxy-1-Diazonio-Pent-1-En-2-Olate
CAS No.	1403-47-0
Molecular Formula	C8H10N3O4-
Molecular Weight	212.18 g/mol (Free acid form)
Synonyms	5-Acetamido-5-carboxy-1-diazoniopent-1-en-2-olate; (Z)-5-Acetamido-5-carboxy-1-diazoniopent-1-en-2-olate; L-2-Amino-5-diazo-4-oxo-5-pentenoic acid acetate; Diazooxonorleucine; DON; 6-Diazo-5-oxo-L-norleucine acetate salt; L-(+)-6-Diazo-5-oxonorleucine acetate
EINECS	Contact for details

Quality Control

Our (Z,5S)-5-Acetamido-5-Carboxy-1-Diazonio-Pent-1-En-2-Olate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee (5S)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.