Description

2-(4-Ethyl-Piperazin-1-Yl)Pyridine-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. This compound matters because it serves as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced materials scientists for drug discovery, catalyst development, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the creation of complex heterocyclic structures.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile building block for creating molecular probes, inhibitors, and tool compounds for biological target validation.
• Catalyst & Ligand Development: Used to synthesize novel piperazine-pyridine based ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential reagent for CROs and CDMOs specializing in bespoke organic synthesis for client projects.

Basic Information

Product Name	2-(4-Ethyl-Piperazin-1-Yl)Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	940285-00-7
Molecular Formula	C17H28BN3O2
Molecular Weight	317.24 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(4-ethylpiperazin-1-yl)pyridine; 2-(4-Ethylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4-Ethyl-1-piperazinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 940285-00-7; 2-(4-Ethylpiperazin-1-yl)pyridine-5-boronic acid pinacol ester; Boronic acid, B-[2-(4-ethyl-1-piperazinyl)-5-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-(4-Ethyl-Piperazin-1-Yl)Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for sensitive cross-coupling applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.