Description

6-Fluoro-1A,2,3,7B-Tetrahydro-1-Oxa-Cyclopropa[A]Naphthalene is a high-purity, advanced pharmaceutical intermediate featuring a unique fused oxa-cyclopropane-naphthalene scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules and complex heterocyclic systems. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fluorinated, fused-ring system.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides and pesticides with enhanced activity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated organic compounds for specialty applications.
• Material Science Research: Investigated as a monomer or precursor for developing novel fluorinated polymers with specific optical or electronic properties.
• Academic & Institutional R&D: Utilized in universities and research institutes for exploring new organic reactions and catalytic methodologies involving strained ring systems.

Basic Information

Product Name	6-Fluoro-1A,2,3,7B-Tetrahydro-1-Oxa-Cyclopropa[A]Naphthalene
CAS No.	939760-65-3
Molecular Formula	C₁₁H₉FO
Molecular Weight	176.19 g/mol
Synonyms	6-Fluoro-1a,2,3,7b-tetrahydro-1-oxacyclopropa[a]naphthalene; 6-Fluoro-1-oxa-2,3-cyclopropanotetralin; 1-Oxa-6-fluorocyclopropa[a]tetralin; 6-Fluoro-1-oxacyclopropa[a]naphthalene; 939760-65-3; FC-939760-65-3; Fluorinated oxa-cyclopropanotetralin; Advanced fluorinated heterocyclic intermediate.
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-1A,2,3,7B-Tetrahydro-1-Oxa-Cyclopropa[A]Naphthalene is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent batch-to-batch quality suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) with full analytical data are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.