Description

7-Fluoro-2,3-Dihydro-1-Benzofuran-3-Amine is a high-purity, fluorinated benzofuran derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile chiral amine intermediate, enabling the development of novel molecules with enhanced biological activity and physicochemical properties. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry, agrochemical research, and material science. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for your sensitive processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the fluorine atom and benzofuran scaffold can contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers and advanced organic electronic materials due to its fused ring structure and amine functionality.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	7-Fluoro-2,3-Dihydro-1-Benzofuran-3-Amine
CAS No.	939757-42-3
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	7-Fluoro-2,3-dihydrobenzofuran-3-amine; 3-Amino-7-fluoro-2,3-dihydrobenzofuran; 7-Fluoro-3-amino-2,3-dihydrobenzofuran; 7-Fluoro-2,3-dihydro-1-benzofuran-3-amine; 939757-42-3; 7-Fluoro-3-aminodihydrobenzofuran; 3-Amino-7-fluoro-2,3-dihydro-1-benzofuran; 7-Fluoro-2,3-dihydrobenzofuran-3-ylamine
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2,3-Dihydro-1-Benzofuran-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.