Description

(2E)-3-(2-Bromo-5-Fluorophenyl)-2-Propenoic Acid is a high-purity, halogenated cinnamic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive α,β-unsaturated carbonyl scaffold with bromo and fluoro substituents, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex heterocyclic compounds.
• Ligand and Catalyst Development: Utilized as a framework for creating novel chelating ligands and organocatalysts in asymmetric synthesis.

Basic Information

Product Name	(2E)-3-(2-Bromo-5-Fluorophenyl)-2-Propenoic Acid
CAS No.	939410-87-4
Molecular Formula	C9H6BrFO2
Molecular Weight	245.05 g/mol
Synonyms	(E)-3-(2-Bromo-5-fluorophenyl)acrylic acid; trans-3-(2-Bromo-5-fluorophenyl)propenoic acid; 2-Bromo-5-fluorocinnamic acid; (E)-2-Bromo-5-fluorocinnamic acid; 3-(2-Bromo-5-fluorophenyl)-2-propenoic acid; (E)-3-(2-Bromo-5-fluorophenyl)acrylic Acid; (2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid; 939410-87-4
EINECS	Contact for details

Quality Control

Our (2E)-3-(2-Bromo-5-Fluorophenyl)-2-Propenoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.