Description

2-2-Dimethyl-4,4,4-Trifluorobutanoic Acid is a specialized fluorinated carboxylic acid building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a tertiary carbon center, makes it a valuable precursor for creating molecules with enhanced metabolic stability and lipophilicity. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group imparts improved activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals with unique surface properties and chemical resistance.
• Chemical Biology Probes: Useful for incorporating fluorine tags into biomolecules for studies using techniques like 19F NMR spectroscopy.

Basic Information

Product Name	2-2-Dimethyl-4,4,4-Trifluorobutanoic Acid
CAS No.	939399-07-2
Molecular Formula	C6H9F3O2
Molecular Weight	170.13 g/mol
Synonyms	4,4,4-Trifluoro-2,2-dimethylbutanoic Acid; 2,2-Dimethyl-4,4,4-trifluorobutanoic Acid; 4,4,4-Trifluoro-2,2-dimethylbutyric Acid; 2,2-Dimethyl-4,4,4-trifluorobutyric Acid; α,α-Dimethyl-β,β,β-trifluorobutyric Acid; 939399-07-2; Butanoic acid, 4,4,4-trifluoro-2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our 2-2-Dimethyl-4,4,4-Trifluorobutanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.