Description

1-Phenylvinylboronic Acid, Neopentyl Glycol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions under demanding conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex biaryl and heterobiaryl scaffolds for active ingredient development.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biaryl structures.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical suppliers performing bespoke synthesis.

Basic Information

Product Name	1-Phenylvinylboronic Acid, Neopentyl Glycol Ester
CAS No.	938080-25-2
Molecular Formula	C13H17BO2
Molecular Weight	216.09 g/mol
Synonyms	1-Phenylvinylboronic Acid Neopentyl Glycol Ester; 2-(1-Phenylethenyl)-5,5-dimethyl-1,3,2-dioxaborinane; Neopentyl (1-Phenylvinyl)boronate; 1-Phenylvinylboronic Acid Pinacol Ester (common misnomer, structurally distinct); (1-Phenylethenyl)boronic Acid Neopentyl Glycol Ester; Vinylbenzene Boronic Acid Neopentyl Ester; B-(1-Phenylvinyl)-5,5-dimethyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 1-Phenylvinylboronic Acid, Neopentyl Glycol Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality systems are designed to support cGMP manufacturing for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.