Description

1H-Indene-3-Carbonitrile, 2-Amino-4,5,6,7-Tetrahydro- is a high-value, heterocyclic organic building block characterized by its fused indene ring system functionalized with both amino and nitrile groups. This unique molecular architecture makes it a critical intermediate for the synthesis of complex pharmacologically active compounds and advanced materials. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, kinase inhibitors, and other therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers, dyes, and organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block in organic chemistry for constructing complex polycyclic structures via cyclization and coupling reactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory research in medicinal chemistry.

Basic Information

Product Name	1H-Indene-3-Carbonitrile, 2-Amino-4,5,6,7-Tetrahydro-
CAS No.	937647-66-0
Molecular Formula	C10H10N2
Molecular Weight	158.20 g/mol
Synonyms	2-Amino-4,5,6,7-tetrahydro-1H-indene-3-carbonitrile; 2-Amino-4,5,6,7-tetrahydroindene-3-carbonitrile; 4,5,6,7-Tetrahydro-2-amino-1H-indene-3-carbonitrile; 3-Cyano-2-amino-4,5,6,7-tetrahydroindene; Tetrahydro-2-aminoindene-3-carbonitrile; 2-Amino-1,2,3,5,6,7-hexahydroindene-4-carbonitrile; 2-Aminotetrahydroindene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1H-Indene-3-Carbonitrile, 2-Amino-4,5,6,7-Tetrahydro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.