Description

5-Iodo-2-Oxo-1-[4-(Trifluoromethyl)Benzyl]-1,2-Dihydro-3-Pyridinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridinecarboxylic acid structure. This compound matters for its critical role as a key building block in the synthesis of novel, targeted small-molecule therapeutics, particularly in oncology and antiviral research. It is primarily needed by R&D scientists and process chemists in pharmaceutical, biotechnology, and fine chemical industries engaged in developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis services catering to the needs of pharmaceutical and biotech clients.
• Library Synthesis: Utilized for generating focused chemical libraries for high-throughput screening against novel biological targets.

Basic Information

Product Name	5-Iodo-2-Oxo-1-[4-(Trifluoromethyl)Benzyl]-1,2-Dihydro-3-Pyridinecarboxylic Acid
CAS No.	937604-36-9
Molecular Formula	C14H9F3INO3
Molecular Weight	423.13 g/mol
Synonyms	1,2-Dihydro-5-iodo-2-oxo-1-[4-(trifluoromethyl)benzyl]-3-pyridinecarboxylic acid; 5-Iodo-1-(4-(trifluoromethyl)benzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 1,2-dihydro-5-iodo-2-oxo-1-[4-(trifluoromethyl)benzyl]-; CAS 937604-36-9
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Oxo-1-[4-(Trifluoromethyl)Benzyl]-1,2-Dihydro-3-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.