Description

1-(2,2-Difluoroethyl)-1H-1,2,4-Triazol-3-Amine is a high-purity, functionalized triazole derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the agrochemical and pharmaceutical sectors, where its unique difluoroethyl-triazole structure enables the creation of compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly for antiviral, antifungal, and anticancer therapies.
• Agrochemical Synthesis: Used in the development of next-generation fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a specialized building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in synthesizing functional polymers or ligands for catalysts and metal-organic frameworks (MOFs).
• Bioconjugation & Probe Development: The amine functional group allows for conjugation, making it useful for creating biochemical probes and diagnostic agents.

Basic Information

Product Name	1-(2,2-Difluoroethyl)-1H-1,2,4-Triazol-3-Amine
CAS No.	937602-83-0
Molecular Formula	C4H6F2N4
Molecular Weight	148.12 g/mol
Synonyms	3-Amino-1-(2,2-difluoroethyl)-1H-1,2,4-triazole; 1H-1,2,4-Triazol-3-amine, 1-(2,2-difluoroethyl)-; 1-(2,2-Difluoroethyl)-1,2,4-triazol-3-amine; 1-(2,2-Difluoroethyl)-3-amino-1,2,4-triazole; DFET Amine; Difluoroethyl Triazole Amine
EINECS	Contact for details

Quality Control

Our production of 1-(2,2-Difluoroethyl)-1H-1,2,4-Triazol-3-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.