Description

3-[3-(Trifluoromethyl)-4,5,6,7-Tetrahydro-2H-Indazol-2-Yl]Butanenitrile is a high-value, advanced pharmaceutical intermediate characterized by its unique indazole core and trifluoromethyl group. This compound is critical for medicinal chemistry research and development, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Serves as a precursor in the creation of potential protease inhibitors due to its specific heterocyclic structure.
• Kinase Inhibitor Synthesis: Employed in the research and development of kinase inhibitors for oncology applications.
• Agrochemical Research: Investigated as an intermediate for developing new active ingredients with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological processes and target validation.

Basic Information

Product Name	3-[3-(Trifluoromethyl)-4,5,6,7-Tetrahydro-2H-Indazol-2-Yl]Butanenitrile
CAS No.	937601-55-3
Molecular Formula	C₁₂H₁₄F₃N₃
Molecular Weight	257.25 g/mol
Synonyms	2-(3-Cyanobutyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-2H-indazole; 3-(Trifluoromethyl)-2-(3-cyanobutyl)-4,5,6,7-tetrahydro-2H-indazole; 3-(3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-2-yl)butanenitrile; 937601-55-3; Butanenitrile, 3-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-2H-indazol-2-yl]-; 3-(3-(Trifluoromethyl)-4,5,6,7-tetrahydro-2H-indazol-2-yl)butyronitrile
EINECS	Contact for details

Quality Control

Our 3-[3-(Trifluoromethyl)-4,5,6,7-Tetrahydro-2H-Indazol-2-Yl]Butanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.