Description

2-(Chroman-8-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it provides a stable, reactive handle for the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex organic molecules. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials. The compound, CAS NO 937591-99-6, is supplied under strict quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by enabling the efficient construction of diverse aromatic scaffolds.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor in the synthesis of advanced organic electronic materials and charge-transport layers.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Polymer and Material Science: Facilitates the incorporation of chroman motifs into polymers and advanced materials to modify physical and optical properties.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological systems and target engagement.

Basic Information

Item	Detail
Product Name	2-(Chroman-8-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	937591-99-6
Molecular Formula	C17H23BO4
Molecular Weight	302.18 g/mol
Synonyms	8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman; Chroman-8-boronic acid pinacol ester; 2-(8-Chromanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 8-Pinacolatoborylchroman; 8-(Pinacolatoboryl)chroman; 8-Boronochroman pinacol ester; Chroman-8-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(Chroman-8-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under a quality management system and undergoes rigorous analytical testing to ensure compliance with stringent industry standards. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to supplying material that meets the exacting requirements for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.