Description

7-Chloroindole-2-Boronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indole-based active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides and fungicides containing functionalized indole scaffolds.
• Material Science: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biological studies.
• Catalyst Ligand Synthesis: Acts as a starting material for preparing specialized ligands used in homogeneous catalysis.
• Custom Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	7-Chloroindole-2-Boronic Acid, Pinacol Ester
CAS No.	936901-92-7
Molecular Formula	C14H17BClNO2
Molecular Weight	277.55 g/mol
Synonyms	7-Chloro-1H-indole-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-chloro-1H-indole; 7-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 7-Chloroindole-2-boronic acid pinacol ester; 7-Chloro-1H-indole-2-boronic acid, pinacol cyclic ester; B-(7-Chloro-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 7-Chloroindole-2-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for HPLC purity, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.