Description

2-Chloro-5-Cyanophenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is essential for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for applications in drug discovery, catalyst development, and the synthesis of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers, where the cyano and chloro functional groups modify electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global chemical industry.

Basic Information

Product Name	2-Chloro-5-Cyanophenylboronic Acid
CAS No.	936249-33-1
Molecular Formula	C7H5BClNO2
Molecular Weight	180.38 g/mol
Synonyms	(2-Chloro-5-cyanophenyl)boronic acid; 2-Chloro-5-cyanobenzeneboronic acid; B-(2-Chloro-5-cyanophenyl)boronic acid; 5-Cyano-2-chlorophenylboronic acid; 936249-33-1; Boronic acid, B-(2-chloro-5-cyanophenyl)-; AKOS005258315
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Cyanophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.