Description

3,3,3-Trifluoropropionaldehyde Hemihydrate, 96% is a high-purity fluorinated aldehyde building block essential for advanced organic synthesis. This compound matters for its ability to introduce the trifluoromethyl group, a key moiety that significantly alters the physicochemical properties of target molecules, enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and coatings with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes to optimize performance and stability.
• Fluorine Chemistry Research: A versatile reagent in academic and industrial laboratories for exploring new fluorination methodologies and creating novel fluorinated compounds.
• Peptide Modification: Used to incorporate fluorinated aldehydes into peptides and peptidomimetics, altering their conformation and interaction with biological targets.

Basic Information

Product Name	3,3,3-Trifluoropropionaldehyde Hemihydrate, 96%
CAS No.	936107-87-8
Molecular Formula	C3H3F3O • ½H2O
Molecular Weight	115.05 g/mol (Anhydrous basis)
Synonyms	3,3,3-Trifluoropropanal Hemihydrate; 2,2,2-Trifluoroethanecarboxaldehyde Hemihydrate; 3,3,3-Trifluoropropionaldehyde Hydrate; 3,3,3-Trifluoropropanal Monohydrate (hemi); TFP Aldehyde Hemihydrate; 3,3,3-Trifluoropropionyl Aldehyde Hydrate; 2,2,2-Trifluoroacetaldehyde Homolog Hemihydrate
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoropropionaldehyde Hemihydrate, 96% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its properties of being easily oxidized and highly volatile. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 96.0%
Water Content (KF)	≤ 3.0%
Related Substances (GC/HPLC)	≤ 1.0% (any single impurity)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.