Description

2-(2-Trifluoromethoxyphenyl)-Isonicotinic Acid is a high-value fluorinated organic intermediate with a distinct molecular architecture. This compound is critical for its role in the synthesis of advanced pharmaceutical and agrochemical agents, where the trifluoromethoxy group imparts desirable metabolic stability and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy moiety enhances biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and drug-target interactions.
• Advanced Material Development: A potential monomer or additive in the research of specialty polymers with unique electronic or surface properties.

Basic Information

Product Name	2-(2-Trifluoromethoxyphenyl)-Isonicotinic Acid
CAS No.	935861-30-6
Molecular Formula	C14H8F3NO3
Molecular Weight	295.22 g/mol
Synonyms	2-[2-(Trifluoromethoxy)phenyl]isonicotinic acid; 2-(2-Trifluoromethoxyphenyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-[2-(trifluoromethoxy)phenyl]-; Isonicotinic acid, 2-(2-trifluoromethoxyphenyl)-; 935861-30-6; 2-(2-(Trifluoromethoxy)phenyl)isonicotinic acid
EINECS	Contact for details

Quality Control

Our production of 2-(2-Trifluoromethoxyphenyl)-Isonicotinic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and meet the exacting standards required for synthetic intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.