Description

1-Bromo-5-Chloro-2-Iodo-4-Methylbenzene is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecular architectures where precise halogen positioning is critical. This compound is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams engaged in the discovery of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the halogen atoms serve as handles for further functionalization.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its halogenated aromatic core.
• Cross-Coupling Reactions: Serves as an excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form complex biaryl and heteroaryl systems.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	1-Bromo-5-Chloro-2-Iodo-4-Methylbenzene
CAS No.	934989-14-7
Molecular Formula	C7H5BrClI
Molecular Weight	331.38 g/mol
Synonyms	2-Bromo-4-Chloro-1-Iodo-5-Methylbenzene; 4-Bromo-2-Chloro-5-Iodotoluene; 5-Chloro-2-Iodo-4-Methyl-1-Bromobenzene; 1-Bromo-5-chloro-2-iodo-4-methyl-benzene; 2-Bromo-4-chloro-1-iodo-5-methyl-benzene; Benzene, 1-bromo-5-chloro-2-iodo-4-methyl-; Toluene, 4-bromo-2-chloro-5-iodo-
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Chloro-2-Iodo-4-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.