Description

4-(5-(2-n-Fmoc Ethyl)-2-Hydroxyphenylazo)Benzoic Acid is a specialized organic compound featuring a benzoic acid core linked to a hydroxyphenylazo moiety and a fluorenylmethyloxycarbonyl (Fmoc) protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a temporary, base-labile protecting agent for amino acids. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of novel peptides, peptidomimetics, and bioconjugates.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for introducing Fmoc-protected amino acid derivatives.
• Pharmaceutical Research & Development: For the synthesis of therapeutic peptide candidates and complex biomolecules.
• Bioconjugation Chemistry: Used to create labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Combinatorial Chemistry Libraries: Serves as a building block for generating diverse arrays of peptide-based compounds for screening.
• Academic Research: Employed in biochemistry and organic chemistry laboratories for studying peptide structure and function.
• Fine Chemical Intermediate: For the custom synthesis of more complex, azo-dye linked or Fmoc-containing molecular architectures.

Basic Information

Product Name	4-(5-(2-n-Fmoc Ethyl)-2-Hydroxyphenylazo)Benzoic Acid
CAS No.	934968-77-1
Molecular Formula	C30H24N2O5
Molecular Weight	492.52 g/mol
Synonyms	4-[5-(2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethyl)-2-hydroxyphenylazo]benzoic acid; Fmoc-protected Azo-Benzoic Acid Derivative; 4-(5-(2-(Fmoc-amino)ethyl)-2-hydroxyphenylazo)benzoic acid; Azo-linked Fmoc-Amino Acid Building Block; CAS 934968-77-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 4-(5-(2-n-Fmoc Ethyl)-2-Hydroxyphenylazo)Benzoic Acid is analyzed to confirm identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity (by IR and NMR), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	Orange to red powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical grade)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.