Description

3,4-Difluoro-2-(2-Fluoro-4-Iodophenylamino)Benzoyl Fluoride is a high-value, multi-fluorinated aromatic building block designed for advanced synthetic chemistry. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex, fluorine-containing target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging fluorine's ability to enhance biological activity and metabolic stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in display and lighting technologies.
• Liquid Crystal & Advanced Polymer Chemistry: Incorporated into the backbone of specialty polymers and liquid crystal molecules to modify electronic and physical properties.
• Cross-Coupling Reactions: The iodine and fluorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring new fluorination methodologies and fluorine's role in material science.

Basic Information

Product Name	3,4-Difluoro-2-(2-Fluoro-4-Iodophenylamino)Benzoyl Fluoride
CAS No.	934664-19-4
Molecular Formula	C13H6F4INO
Molecular Weight	403.09 g/mol
Synonyms	2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoyl fluoride; 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoyl fluoride; Benzoyl fluoride, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-; 934664-19-4; 2-Amino-3,4-difluorobenzoyl fluoride derivative; N-(2-Fluoro-4-iodophenyl)-3,4-difluoroanthraniloyl fluoride
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-(2-Fluoro-4-Iodophenylamino)Benzoyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.