Description

1H-Pyrazole, 1-Propyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized pyrazole derivative containing a pinacol boronate ester group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boron-containing coupling partner for the synthesis of biaryl and heterobiaryl structures, a fundamental reaction in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Acts as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Utilized as a probe or linker in the study of biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, complex pyrazole-based architectures.

Basic Information

Item	Details
Product Name	1H-Pyrazole, 1-Propyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	934586-51-3
Molecular Formula	C₁₂H₂₁BN₂O₂
Molecular Weight	236.12 g/mol
Synonyms	1-Propyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-propyl-1H-pyrazole; 1-Propyl-1H-pyrazole-3-boronic acid pinacol ester; 1-Propyl-3-pyrazoleboronic acid pinacol ester; 1-Propyl-1H-pyrazol-3-ylboronic acid pinacol ester; 3-Borono-1-propyl-1H-pyrazole pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 1H-Pyrazole, 1-Propyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for advanced synthetic applications. Our quality management system supports the provision of comprehensive Certificates of Analysis (COA) for traceability and compliance. We adhere to industry best practices and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.