Description

n-Methyl-n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Propan-2-Amine is a high-value, functionalized boronic ester derivative designed for advanced synthetic chemistry. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl amine motifs.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester group is utilized for palladium-catalyzed coupling reactions to form biaryl and other carbon-carbon bonds.
• Ligand and Catalyst Development: The amine functionality allows for its use in designing novel ligands for metal catalysts.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	n-Methyl-n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Propan-2-Amine
CAS No.	934586-48-8
Molecular Formula	C17H28BNO2
Molecular Weight	289.22 g/mol
Synonyms	N-Methyl-N-[(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]propan-2-amine; 2-((Isopropyl(methyl)amino)methyl)phenylboronic acid pinacol ester; 2-((Methyl(propan-2-yl)amino)methyl)phenylboronic acid pinacol ester; N-Isopropyl-N-methyl-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]amine; 934586-48-8; CAS 934586-48-8
EINECS	Contact for details

Quality Control

Our n-Methyl-n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Propan-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.