Description

n-[4-Methoxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]-n-Methylpropan-2-Amine is a sophisticated boronic ester derivative, a key building block in modern synthetic chemistry. Its primary value lies in its role as a versatile intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, functionalized intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic architectures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Employed in the design and synthesis of molecular probes and drug candidates targeting various biological pathways.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	n-[4-Methoxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]-n-Methylpropan-2-Amine
CAS No.	934586-45-5
Molecular Formula	C18H30BNO3
Molecular Weight	319.25 g/mol
Synonyms	N-[4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]-N-methylpropan-2-amine; 2-[4-Methoxy-3-[[methyl(propan-2-yl)amino]methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Isopropylmethyl[4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]amine; Pinacol [4-Methoxy-3-[(methyl(1-methylethyl)amino)methyl]phenyl]boronate; 934586-45-5; Boronic ester intermediate
EINECS	Contact for details

Quality Control

Every batch of our n-[4-Methoxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]-n-Methylpropan-2-Amine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive applications like pharmaceutical R&D. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.