Description

3-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylic Acid is a high-value, multifunctional heterocyclic building block featuring both a carboxylic acid and a protected aldehyde group. This compound matters for its versatility as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and advanced material research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the thiophene moiety imparts specific biological activity.
• Material Science Research: Acts as a building block for creating functional polymers, organic semiconductors, and liquid crystals due to its conjugated thiophene system.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules, leveraging the reactivity of both the carboxylic acid and the acetal-protected aldehyde functional groups.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis and in the development of organocatalysts.

Basic Information

Product Name	3-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylic Acid
CAS No.	934570-44-2
Molecular Formula	C9H8O4S
Molecular Weight	212.22 g/mol
Synonyms	2-Thiophenecarboxylic acid, 3-(1,3-dioxolan-2-yl)-; 3-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic acid; 3-(2-Thienyl)-1,3-dioxolane-2-carboxylic acid; 3-(1,3-Dioxolan-2-yl)-2-thiophenecarboxylic acid; 934570-44-2; Thiophene-2-carboxylic acid, 3-(1,3-dioxolan-2-yl)-; 3-(Dioxolan-2-yl)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The product may be hygroscopic; handle and store under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.