Description

1-[4-(4,4,6-Trimethyl-1,3,2-Dioxaborinan-2-Yl)Phenyl]Ethan-1-One is a high-value organoboron building block, specifically a pinacol-protected aryl ketone boronic ester. This compound is critical for modern synthetic chemistry, enabling precise carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and conjugated systems in drug discovery and material science.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-ketone motifs.
• Ligand and Catalyst Development: Employed in the creation of novel organometallic complexes and catalytic systems.
• Polymer and Material Science: A building block for synthesizing specialty polymers, organic electronic materials, and liquid crystals.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Used as a linker or functional component in the design of bifunctional molecules.

Basic Information

Product Name	1-[4-(4,4,6-Trimethyl-1,3,2-Dioxaborinan-2-Yl)Phenyl]Ethan-1-One
CAS No.	934558-34-6
Molecular Formula	C15H21BO3
Molecular Weight	260.14 g/mol
Synonyms	4-Acetylphenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone; 4-Acetylbenzeneboronic acid pinacol ester; 4-Acetylphenyl-Bpin; (4-Acetylphenyl)boronic acid pinacol ester; 4-Acetylbenzeneboronic acid, cyclic ester with pinacol; 2-[4-Acetylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 1-[4-(4,4,6-Trimethyl-1,3,2-Dioxaborinan-2-Yl)Phenyl]Ethan-1-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.