Description

7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Boronic Acid Pinacol Ester is a high-value, multi-functional chemical building block, specifically a protected boronic acid derivative. Its core value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science, where precise molecular assembly is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted cancer therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boron-containing partner for forming carbon-carbon bonds, a cornerstone of modern medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic frameworks.
• Material Science: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	934178-97-9
Molecular Formula	C19H22BN3O4S
Molecular Weight	399.27 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-5-boronic acid, 7-[(4-methylphenyl)sulfonyl]-, 1,1-dimethylethyl ester; 7-Tosyl-7H-pyrrolo[2,3-d]pyrimidin-5-ylboronic acid pinacol ester; 934178-97-9; BRN 15361559; 5-Boronic acid pinacol ester-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.