Description

Benzamide, n-(Difluoromethyl)-n-Methyl- is a specialized fluorinated organic compound with the CAS registry number 933994-74-2. This high-value intermediate is critical for introducing the difluoromethyl group into complex molecular architectures, a key modification in modern synthetic chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active ingredients and agrochemicals, where its unique structural motif can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance efficacy and environmental profile.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis: Employed as a versatile reagent in cross-coupling reactions and for the construction of complex heterocycles in academic and industrial R&D settings.
• Fluorine Chemistry Library: An essential component for creating focused screening libraries in drug discovery programs exploring fluorinated chemical space.

Basic Information

Product Name	Benzamide, n-(Difluoromethyl)-n-Methyl-
CAS No.	933994-74-2
Molecular Formula	C9H9F2NO
Molecular Weight	185.17 g/mol
Synonyms	N-Methyl-N-(difluoromethyl)benzamide; N-(Difluoromethyl)-N-methylbenzamide; Benzamide, N-(difluoromethyl)-N-methyl-; Difluoromethyl-methyl-benzamide; N-Methyl-N-difluoromethylbenzamide; N-Difluoromethyl-N-methylbenzamide
EINECS	Contact for details

Quality Control

Every batch of Benzamide, n-(Difluoromethyl)-n-Methyl- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA), including results for purity (HPLC), identity (IR, NMR), and impurity profile, is supplied with each shipment to guarantee reproducible performance and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.