Description

2-(4-Fluorophenyl)-5-Methyl-3H-Imidazole-4-Carboxylic Acid is a high-purity fluorinated imidazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with tailored biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in therapeutic areas targeting enzymes and receptors where the imidazole core is pharmacologically active.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the fluorophenyl moiety can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for synthesizing functional organic materials, including dyes, pigments, and polymers with specific electronic properties.
• Chemical Biology Probes: Utilized in constructing molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	2-(4-Fluorophenyl)-5-Methyl-3H-Imidazole-4-Carboxylic Acid
CAS No.	933751-61-2
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	4-Fluoro-α-methyl-1H-imidazole-5-acetic acid (alternative interpretation); 5-Methyl-2-(4-fluorophenyl)-1H-imidazole-4-carboxylic acid; 2-(p-Fluorophenyl)-5-methyl-1H-imidazole-4-carboxylic acid; 4-Carboxy-5-methyl-2-(4-fluorophenyl)imidazole; 933751-61-2; Fluorophenyl methyl imidazole carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-5-Methyl-3H-Imidazole-4-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects requiring compliance with ISO, cGMP, and REACH standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.