Description

Methyl 3-Amino-3-[4-(Trifluoromethyl)Phenyl]Propanoate CAS NO 933674-13-6 is a high-value, non-natural amino acid ester derivative featuring a trifluoromethylphenyl group, which imparts unique physicochemical properties. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for introducing fluorine-containing motifs. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where its structure can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially in CNS and oncology therapeutic areas.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Incorporation into peptide analogs to study structure-activity relationships and improve proteolytic stability.
• Material Science Precursor: Intermediate for synthesizing specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and fluorescent tags used in biochemical assays.

Basic Information

Product Name	Methyl 3-Amino-3-[4-(Trifluoromethyl)Phenyl]Propanoate
CAS No.	933674-13-6
Molecular Formula	C11H12F3NO2
Molecular Weight	247.21 g/mol
Synonyms	Methyl 3-amino-3-[4-(trifluoromethyl)phenyl]propionate; 3-Amino-3-(4-trifluoromethylphenyl)propionic acid methyl ester; β-Amino-β-(4-trifluoromethylphenyl)propionic acid methyl ester; Methyl β-amino-β-(4-(trifluoromethyl)phenyl)propanoate; (R/S)-Methyl 3-amino-3-(4-(trifluoromethyl)phenyl)propanoate; 933674-13-6; 4-(Trifluoromethyl)-β-alanine methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-3-[4-(Trifluoromethyl)Phenyl]Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.