Description

3-Fluoro-5-Iodobenzaldehyde Dimethyl Acetal is a versatile and highly functionalized aromatic building block, specifically a protected aldehyde derivative. This compound is of significant value in advanced organic synthesis, where it serves as a key precursor for constructing complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications in cross-coupling reactions and as a scaffold for drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and iodinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the unique halogen pattern influences bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for catalysis and molecular recognition studies.
• Chemical Biology Probes: Acts as a building block for fluorescent tags or molecular probes used in diagnostic and imaging applications.

Basic Information

Product Name	3-Fluoro-5-Iodobenzaldehyde Dimethyl Acetal
CAS No.	933672-24-3
Molecular Formula	C9H10FIO2
Molecular Weight	296.08 g/mol
Synonyms	1-Fluoro-3-iodo-5-(dimethoxymethyl)benzene; Benzene, 1-fluoro-3-iodo-5-(dimethoxymethyl)-; 3-Fluoro-5-iodobenzaldehyde dimethyl acetal; (3-Fluoro-5-iodophenyl)dimethoxymethane; 3-Fluoro-5-iodobenzaldehyde, dimethyl acetal; Dimethyl (3-fluoro-5-iodobenzylidene) acetal
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Iodobenzaldehyde Dimethyl Acetal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.