Description

(S)-1-(4-Fluorophenyl)Aziridine-2-Carboxamide is a high-purity chiral aziridine derivative, a critical building block in modern asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with precise stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective reactions.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and the development of molecular probes due to its reactive aziridine ring.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique optical or mechanical properties.

Basic Information

Product Name	(S)-1-(4-Fluorophenyl)Aziridine-2-Carboxamide
CAS No.	933453-50-0
Molecular Formula	C9H9FN2O
Molecular Weight	180.18 g/mol
Synonyms	(2S)-1-(4-Fluorophenyl)aziridine-2-carboxamide; (S)-1-(p-Fluorophenyl)aziridine-2-carboxamide; (S)-1-(4-Fluorophenyl)-2-carbamoylaziridine; 933453-50-0; (S)-Aziridine-2-carboxamide, 1-(4-fluorophenyl)-; 1-(4-Fluorophenyl)-(S)-aziridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our (S)-1-(4-Fluorophenyl)Aziridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a desiccator to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.