Description

(1S,3R)-3-Fluorocyclopentan-1-Amine CAS NO 932779-47-0 is a chiral fluorinated cyclopentylamine building block of significant interest in modern pharmaceutical and agrochemical research. This compound matters because its unique stereochemistry and fluorine atom introduce desirable metabolic stability and binding affinity into target molecules. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Peptidomimetics & Bioisosteres: The fluorinated cyclopentane ring acts as a rigid, metabolically stable scaffold to replace peptide bonds or other functional groups in drug design.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	(1S,3R)-3-Fluorocyclopentan-1-Amine
CAS No.	932779-47-0
Molecular Formula	C5H10FN
Molecular Weight	103.14 g/mol
Synonyms	(1S,3R)-3-Fluorocyclopentanamine; (1S,3R)-3-Fluoro-1-cyclopentanamine; 3-Fluorocyclopentan-1-amine, (1S,3R)-; (1S,3R)-3-Fluorocyclopentylamine; (1S,3R)-3-F-CPA; trans-3-Fluorocyclopentan-1-amine; (1S,3R)-rel-3-Fluorocyclopentan-1-amine; 932779-47-0
EINECS	Contact for details

Quality Control

Our (1S,3R)-3-Fluorocyclopentan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and GC/HPLC for chemical purity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.