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N,n-Diethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide CAS NO 932382-18-8


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CAS No.:932382-18-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,n-Diethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide is a high-value organoboron building block, specifically a picolinamide-substituted boronic ester. This compound is essential for modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

  • Suzuki-Miyaura Cross-Coupling Reagent: A key intermediate for forming carbon-carbon bonds in the synthesis of complex heterocycles and biaryl structures prevalent in drug discovery.
  • Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing substituted pyridine cores.
  • Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
  • Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs or conductive polymers.
  • Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
  • Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name N,n-Diethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide
CAS No. 932382-18-8
Molecular Formula C18H29BN2O3
Molecular Weight 332.25 g/mol
Synonyms 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethylpicolinamide; 2-Pyridinecarboxamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethyl-; N,N-Diethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethyl-2-pyridinecarboxamide; Boronic ester picolinamide derivative; Pinacol boronate picolinamide
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Quality Control

Every batch of our N,n-Diethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide is produced and tested under strict quality management systems. We ensure high purity and lot-to-lot consistency through advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity during use. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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