Description

N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Acetamide is a high-value, multi-functional chemical building block that integrates a pyrazole core with a pinacol boronate ester and an acetamide moiety. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyrazole-boronate structure allows for the introduction of diverse aromatic systems.
• Material Science: Serves as a precursor for creating functional organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura coupling to form carbon-carbon bonds, facilitating the synthesis of biaryl and heterobiaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Library Synthesis: An important reagent for combinatorial and parallel synthesis in high-throughput screening to generate diverse compound libraries.

Basic Information

Product Name	N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Acetamide
CAS No.	930596-20-6
Molecular Formula	C13H22BN3O3
Molecular Weight	279.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide, N,N-dimethyl-; 1H-Pyrazole-1-acetamide, N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; N,N-Dimethyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetamide; 4-(Pinacolatoboryl)-1H-pyrazole-1-acetamide, N,N-dimethyl-; 930596-20-6; N,N-Dimethyl-4-(pinacolatoboron)-1H-pyrazole-1-acetamide
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.