Description

4-Fluoro-3-(Phenoxymethyl)-1-Benzothiophene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzothiophene core functionalized with fluorine and phenoxymethyl groups. This compound is of critical importance for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Serves as a key building block in the pilot-scale and commercial-scale production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition or receptor modulation due to its specific structural features.
• Organic Synthesis: Employed in advanced organic synthesis for constructing complex heterocyclic molecules in academic and industrial settings.

Basic Information

Product Name	4-Fluoro-3-(Phenoxymethyl)-1-Benzothiophene-2-Carboxylic Acid
CAS No.	929974-17-4
Molecular Formula	C₁₆H₁₁FO₃S
Molecular Weight	302.32 g/mol
Synonyms	4-Fluoro-3-(phenoxymethyl)benzo[b]thiophene-2-carboxylic acid; 4-Fluoro-3-phenoxymethyl-1-benzothiophene-2-carboxylic acid; 1-Benzothiophene-2-carboxylic acid, 4-fluoro-3-(phenoxymethyl)-; 929974-17-4; 4-Fluoro-3-phenoxymethylbenzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(Phenoxymethyl)-1-Benzothiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All materials are manufactured and handled in a controlled environment. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity confirmation, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.