Description

3-[3-(Trifluoromethyl)[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl]-1H-Indole is a high-value, structurally complex heterocyclic compound featuring a fused triazolothiadiazole core and an indole moiety, distinguished by the presence of a trifluoromethyl group. This molecular architecture makes it a critical advanced intermediate for research and development in modern agrochemical and pharmaceutical discovery programs. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly those targeting specific biological pathways where its unique scaffold can impart enhanced activity, metabolic stability, and bioavailability.

Application

• Agrochemical Intermediate: A key building block for the synthesis of novel fungicides, herbicides, and insecticides, leveraging the bioactivity of the triazolothiadiazole and indole structures.
• Pharmaceutical Research: Serves as a privileged scaffold in medicinal chemistry for developing potential drug candidates targeting various enzymes and receptors in oncology, neurology, and anti-infective therapy.
• Chemical Biology Probe: Used in academic and industrial research to study protein-ligand interactions and biological mechanisms due to its specific three-dimensional shape and electronic properties.
• Material Science Research: Investigated as a precursor for specialty polymers or organic electronic materials where its fused ring system and fluorine content may confer desirable thermal stability or electronic characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular entity.

Basic Information

Product Name	3-[3-(Trifluoromethyl)[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl]-1H-Indole
CAS No.	929831-38-9
Molecular Formula	C₁₂H₆F₃N₅S
Molecular Weight	309.27 g/mol
Synonyms	1H-Indole, 3-[3-(trifluoromethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-; 3-(3-(Trifluoromethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-1H-indole; 6-(1H-Indol-3-yl)-3-(trifluoromethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole; 929831-38-9; 3-(3-Trifluoromethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-indole; Fused triazolothiadiazole-indole derivative
EINECS	Contact for details

Quality Control

Every batch of 3-[3-(Trifluoromethyl)[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl]-1H-Indole is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Standard analytical techniques including HPLC, NMR, and MS are employed to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.