Description

3-Methoxycarbonyl-5-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid ester crucial for modern synthetic organic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, a cornerstone of medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Serves as a key intermediate in creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and organometallic complexes.
• Material Science Research: Used in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Chemical Biology Probes: Facilitates the labeling and modification of biomolecules for research and diagnostic applications.

Basic Information

Product Name	3-Methoxycarbonyl-5-Methylphenylboronic Acid Pinacol Ester
CAS No.	929626-17-5
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	5-Methyl-3-(methoxycarbonyl)phenylboronic acid pinacol ester; (3-(Methoxycarbonyl)-5-methylphenyl)boronic acid pinacol ester; Methyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 3-Carbomethoxy-5-methylphenylboronic acid pinacol ester; Boronic acid, B-[3-(methoxycarbonyl)-5-methylphenyl]-, 1,1-dimethylethyl ester; 929626-17-5; Methyl 3-methyl-5-(pinacolatoboryl)benzoate
EINECS	Contact for details

Quality Control

Our 3-Methoxycarbonyl-5-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.