Description

2-(3-Chloro-5-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective carbon-carbon bond formation, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific chlorinated, methoxy-substituted aromatic structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the global life sciences industry.

Basic Information

Item	Details
Product Name	2-(3-Chloro-5-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	929626-16-4
Molecular Formula	C13H18BClO3
Molecular Weight	268.54 g/mol
Synonyms	(3-Chloro-5-methoxyphenyl)boronic acid pinacol ester; 3-Chloro-5-methoxybenzeneboronic acid pinacol ester; 3-Chloro-5-methoxyphenylboronic acid pinacol ester; Pinacol (3-chloro-5-methoxyphenyl)boronate; 929626-16-4; 2-(3-Chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloro-5-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is produced and tested under strict quality management protocols to ensure consistency and purity for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.