Description

4-Bromo-2-Chloro-6-Fluoro-Benzaldehyde is a halogenated benzaldehyde derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a precursor in the development of new herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as liquid crystals and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-Bromo-2-Chloro-6-Fluoro-Benzaldehyde
CAS No.	929621-33-0
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	2-Chloro-4-bromo-6-fluorobenzaldehyde; 6-Fluoro-2-chloro-4-bromobenzaldehyde; Benzaldehyde, 4-bromo-2-chloro-6-fluoro-; 4-Bromo-2-chloro-6-fluorobenzenecarboxaldehyde; 929621-33-0; 4-Br-2-Cl-6-F-C6H2CHO
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Fluoro-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.