Description

2-Chloro-1-(2,6-Difluorophenyl)Ethan-1-One is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and difluoro substituents, makes it a versatile and reactive intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. We supply this material with a commitment to consistent quality and reliable global availability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the biological activity of the difluorophenyl moiety.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers and functional materials.
• Chemical Synthesis: A versatile electrophile in Friedel-Crafts acylation and nucleophilic substitution reactions for introducing functionalized acetyl groups.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and for custom synthesis projects in CRO (Contract Research Organization) settings.

Basic Information

Product Name	2-Chloro-1-(2,6-Difluorophenyl)Ethan-1-One
CAS No.	929249-84-3
Molecular Formula	C8H5ClF2O
Molecular Weight	190.57 g/mol
Synonyms	2-Chloro-1-(2,6-difluorophenyl)ethanone; 2',6'-Difluoro-2-chloroacetophenone; 2-Chloro-2',6'-difluoroacetophenone; α-Chloro-2,6-difluoroacetophenone; 1-(2,6-Difluorophenyl)-2-chloroethanone; 2-Chloro-1-(2,6-difluorophenyl)ethan-1-one; (2,6-Difluorophenyl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2,6-Difluorophenyl)Ethan-1-One is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture ingress and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.